我国联合培养博士生的演进、向度与展望——基于巴斯德象限的视角     

刘贤伟  高飞  邹洋 《中国高教研究》2021,(1):89-95

《教育规划纲要》颁布实施以来,我国博士生教育中的联合培养实践进入了快速发展的时期。科技政策领域的巴斯德象限模型为解释我国联合培养博士生工作的相关政策和发展动向提供了一个逻辑框架,从巴斯德象限模型的视角出发,对《教育规划纲要》实施十年以来我国国家层面推动的高校与(工程)科研院所联合培养博士生项目、协同创新中心项目、博士专业学位联合培养等实践开展及相关政策进行梳理总结,进一步提出我国联合培养博士生体系的象限模型,并据此分析我国联合培养博士生体系的核心向度与未来发展方向。  相似文献   

地质超前预报系统在栋梁坡隧道施工中的应用     

刘倩  檀朝彬  韩星  吕会喜  展先彪 《实验室研究与探索》2021,(2):43-48

基于地震反射波法超前预测系统的原理及主要技术手段,以栋梁坡隧道工程为实例,针对隧道复杂的地质条件,施工过程中将超前地质预报和地质素描调查相结合,先对隧道全段范围内地形、地层岩性等进行全面核查,然后结合核查结果运用地震反射波法预报掌子面前方的节理裂隙发育情况,围岩完整性等地质信息。开挖后验证情况与预测结果基本一致,为后续预防突水塌方等隧道地质灾害事故的发生提供数据支撑,有效保证栋梁坡隧道的施工安全。  相似文献   

晋绥抗日根据地农业研究     

王明前 《苏州教育学院学报》2021,(1)

晋绥边区党和政府把农业作为战时经济的主体重点加以经营,在恢复正常生产的基础上,进一步挖掘农业生产潜力。边区党和政府积极鼓励垦荒事业,专门制定法令进行政策扶持,通过经济杠杆作用奖励发动民间力量兴办水利事业。同时,帮助农民提高农业生产技术,奖励某些特产的种植,增加农业的综合效益。畜牧业也得到大力扶持。边区粮政是农业生产成就的具体实现,也是边区财政制度的重要组成。边区党和政府严格执行粮食财政的预决算制度,规范粮食的支出程序,逐步完善粮食财政制度,并采取政府赈济和民间借粮相结合的办法,调剂粮食资源。  相似文献   

What emotional-centred challenges do children attending special schools face over primary–secondary school transition?     

Charlotte L. Bagnall  Claire L. Fox  Yvonne Skipper 《Journal of Research in Special Educational Needs》2021,21(2):156-167

Primary–secondary school transition encompasses multiple social, academic and environmental changes which can negatively impact children’s emotional well-being. Children with Social, Emotional and Mental Health difficulties (SEMH) are believed to be especially vulnerable during this time. However, the voices of children with SEMH are heavily underrepresented in this field within practice and research. The present case study examined how children with SEMH difficulties within one special school experience primary–secondary school transition and how they are supported, in order to make recommendations to improve this period. The case study was qualitative and longitudinal, conducted over 18-months and methodologies included ethnographic observations, child photo-elicitation focus groups (with 11 Year 6 children) and three adult interviews. Findings demonstrated that over primary–secondary school transition children with SEMH difficulties (a) negotiate significant structural changes in support (often unanticipated) and (b) need to feel a sense of safety and belonging. To manage this effectively, transition provision for children with SEMH difficulties needs to consider their short-term emotional well-being whilst still in primary school, in addition to their long-term well-being looking ahead to secondary school. Greater collaboration and communication across schools and stakeholders can help ensure children receive continuity in standards and support.  相似文献   

风雨耦合作用下的城市道路行车风险评估          下载免费PDF全文

张可欣岳小泉孙晓楠方敬升黄海南游宇光 《福建工程学院学报》2021,(1):75-80

从道路条件、天气条件和设施条件3个方面选取18个影响因素,基于DAMATEL方法,建立直接影响矩阵并规范化,获得综合影响矩阵,得到三层次风雨耦合作用下的城市道路风险评估体系,结合模糊综合评价以及层次分析法确定各级评价指标的权重,建立了一个相对完整的评价体系,并将其应用于当地的风险评估中,为当地的交通管理控制以及降低行车风险提供了一定的理论参考。  相似文献   

大数据时代大学生自主学习能力预测研究     

郝水侠  付敏 《教育技术导刊》2021,19(12):32-37

大数据时代知识增长速度呈指数级增长,提升大学生自主学习能力迫在眉睫。根据大学生自主学习能力调查问卷,利用马尔可夫链构建大学生自主学习能力预测模型,通过模糊综合评判法对大学生自主学习能力进行评估,并对实验结果进行分析比较,给出不同年级、不同性别以及学习动机对自主学习能力的影响,最后给出大学生提升自主学习能力的方法与建议。  相似文献   

CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement     

Li  Chao  Brant  Eleanor  Budak  Hikmet  Zhang  Baohong 《Journal of Zhejiang University. Science. B》2021,22(4):253-284

Since it was first recognized in bacteria and archaea as a mechanism for innate viral immunity in the early 2010 s,clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein(Cas) has rapidly been developed into a robust, multifunctional genome editing tool with many uses. Following the discovery of the initial CRISPR/Cas-based system, the technology has been advanced to facilitate a multitude of different functions. These include development as a base editor, prime editor, epigenetic editor, and CRISPR interference(CRISPRi) and CRISPR activator(CRISPRa) gene regulators. It can also be used for chromatin and RNA targeting and imaging. Its applications have proved revolutionary across numerous biological fields, especially in biomedical and agricultural improvement. As a diagnostic tool, CRISPR has been developed to aid the detection and screening of both human and plant diseases, and has even been applied during the current coronavirus disease 2019(COVID-19) pandemic. CRISPR/Cas is also being trialed as a new form of gene therapy for treating various human diseases, including cancers, and has aided drug development. In terms of agricultural breeding, precise targeting of biological pathways via CRISPR/Cas has been key to regulating molecular biosynthesis and allowing modification of proteins, starch, oil, and other functional components for crop improvement. Adding to this, CRISPR/Cas has been shown capable of significantly enhancing both plant tolerance to environmental stresses and overall crop yield via the targeting of various agronomically important gene regulators. Looking to the future, increasing the efficiency and precision of CRISPR/Cas delivery systems and limiting off-target activity are two major challenges for wider application of the technology. This review provides an in-depth overview of current CRISPR development, including the advantages and disadvantages of the technology,recent applications, and future considerations.  相似文献   

Genome-wide analysis of microRNA156 and its targets,the genes encoding SQUAMOSA promoter-binding protein-like (SPL) transcription factors,in the grass family Poaceae     

Yue  Erkui  Tao  Hua  Xu  Jianhong 《Journal of Zhejiang University. Science. B》2021,22(5):366-382

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Evaluation and application of an efficient plant DNA extraction protocol for laboratory and field testing     

Qi WANG  Xiaoxia SHEN  Tian QIU  Wei WU  Lin LI  Zhi'an WANG  Huixia SHOU 《Journal of Zhejiang University. Science. B》2021,22(2):99

Nucleic acids in plant tissue lysates can be captured quickly by a cellulose filter paper and prepared for amplification after a quick purification.In this study,a published filter paper strip method was modified by sticking the filter paper on a polyvinyl chloride resin(PVC)sheet.This modified method is named EZ-D,for EASY DNA extraction.Compared with the original cetyl trimethylammonium bromide(CTAB)method,DNA extracted by EZ-D is more efficient in polymerase chain reaction(PCR)amplification due to the more stable performance of the EZ-D stick.The EZ-D method is also faster,easier,and cheaper.PCR analyses showed that DNA extracted from several types of plant tissues by EZ-D was appropriate for specific identification of biological samples.A regular PCR reaction can detect the EZ-D-extracted DNA template at concentration as low as 0.1 ng/μL.Evaluation of the EZ-D showed that DNA extracts could be successfully amplified by PCR reaction for DNA fragments up to 3000 bp in length and up to 80%in GC content.EZ-D was successfully used for DNA extraction from a variety of plant species and plant tissues.Moreover,when EZ-D was combined with the loop-mediated isothermal amplification(LAMP)method,DNA identification of biological samples could be achieved without the need for specialized equipment.As an optimized DNA purification method,EZ-D shows great advantages in application and can be used widely in laboratories where equipment is limited and rapid results are required.  相似文献   

QFD理论在高校创新创业教育课程设计中的应用研究     

范闾翮 《当代教育理论与实践》2021,13(1):79-86

我国当前高校创新创业教育课程存在一定的不足,尽管有研究提出了改进对策或建议,但其提出过程缺少科学系统的分析工具,且所提出的对策措施千校一面,缺乏针对性。造成这种状况的本质原因在于未对课程对象(顾客)需求期望进行清晰准确的识别。质量功能展开(QFD)立足于顾客,能有效将顾客需求转化为产品/服务设计要求。因此,将QFD与高校双创课程设计相结合,提出创新创业课程质量功能展开模型(ICQFDM),通过"顾客需求—教学规划"与"教学规划—教学管理"两级质量屋,将顾客对于双创课程的要求转化到课程设计要求中。以南京已开展创新创业课程且互为竞争对手的2所财经类院校为例,演示模型的具体运用过程。结果显示:2所高校创新创业课程设计路径存在较大差异。ICQFDM的提出为高校建设创新创业课程提供了可操作的分析框架,各高校可结合不同实际情况,制定适用于自身的课程建设措施。  相似文献